Cell biology of cancer

Arbeitsgruppe Prof. Dr. med. Bassermann

Research in our lab focuses on the molecular pathophysiology and evolution of malignant diseases, particulary hematological neoplasms, such as B-cell malignancies and acute leukemias, as well as selected solid entities including lung cancer.

Research Interests

Research in our lab focuses on the molecular pathophysiology and evolution of malignant diseases, particularly hematological neoplasms, such as B-cell malignancies and acute leukemias, as well as selected solid entities including lung cancer. Functionally, we focus on aberrant ubiquitin-dependent signaling pathways and other posttranslational mechanisms, which play pivotal roles in the regulation of tumorrelevant cellular processes such as cell cycle regulation, DNA damage response, immune responses, cell metabolism and programmed cell death.

Starting from a discovery-driven approach that combines multi-OMIC technologies (tumor genomics and functional proteomics) with cell biology, preclinical mouse models and analyses in large, defined patient cohorts, our central task is to forward our new functional insights to direct translational application. To this end, we define and validate new therapeutic target structures and engage in respective drug development efforts, either in academia or in collaboration with pharmaceutical companies, to develop new treatment strategies that are investigated in early clinical trials.

Principal Investigator
Prof. Dr. med. Florian Bassermann
E-Mail(link sends e-mail)

Laboratory:
Center for Translational Cancer Research (TranslaTUM)


Lab Members (alphabetical)

Nicolas Barbian

MD Student


Michael Dietachmayr

MD


Antje Gabriel

Antje Gabriel

PhD student


Michael Heider

Dr. med. Michael Heider

Clinician scientist


Kilian Irlinger


Marisa Kurz

Marisa Kurz

MD student


Abirami Rathakrishnan

Abirami Rathakrishnan

Technician


Leonie Rieger

Leonie Rieger

PhD, Postdoc


Isabell Schäffer

Isabell Schäffer

Technician


Petra Schenk

Petra Schenk

Technician


Tobias Schulze

Tobias Schulze

PhD student


Ria Spallek

Ria Spallek

PhD student


Anna Kuisl

Anna Sperk

PhD student


Jacob Stroh

Jacob Stroh

MD student


Marlene Tietje

Marlene Tietje

MD


Vinona Wagner

Vinona Wagner

PhD student



Alumni


Ursula Baumann, Dr. rer. nat

Philipp Blüm, Dr. med.

Krischan Braitsch, Dr. med.

David Brockelt, Dr. rer. nat

Andrä Brunner

Katharina Clemm von Hohenberg, Dr. med.

Carina Dürr

Ruth Eichner, Dr. med, PhD

Vanesa Fernández-Sáiz, PhD

Laura Häusler, Dr. med.

Oleksandra Karpiuk, Dr. rer. nat.

Anna-Maria Knorn

Julia Kurutz

Sophie Langer

Felicia Loewecke, Dr. med.

Clemens Reiter

Carmen Richter Dr. rer. nat

Sonja Schroeder

Chuan Shan, PhD

Claudia Sturm

Bianca-Sabrina Targosz, Dr. rer. nat.

Knut Thiele

Michaela Walzik

Application

Written applications including CV are welcome and should be forwarded by e-mail(link sends e-mail) to Prof. Florian Bassermann.

 

Third party funding
EU-ERC Consolidator Grant

DFG – Research Center SFB1243 (link is external)
DFG – Research Center SFB 1335
Wilhelm Sander Stiftung

 

Ihr Ansprechpartner

   

Prof. Dr. med.
Florian Bassermann
Principal Investigator

Laboratory: TranslaTUM

E-Mail(link sends e-mail)